Safe Medications in Pregnancy


  • Loratadine (Claritin), Cetirizine (Zyrtec), Fexofenadine (Allegra) without “D”
  • Diphenhydramine (Benadryl)
  • Saline nasal rinses or Neti Pot
  • Fluticasone nasal spray (Flonase)


  • Many antibiotics are safe to take in pregnancy. The most common that we recommend are Amoxicillin and Cephalexin. You may be prescribed other antibiotics depending on what we are treating, in most instances the benefits of these antibiotics outweigh the risks. If you have questions, we recommend you speak with your provider.


  • Tamiflu–Rx only, speak with your provider
  • Paxlovid–Rx only, speak with your provider
  • Valtrex—Rx only, speak with your provider


  • Acetaminophen (Tylenol)
  • Guaifenesin (Mucinex)
  • Dextromethorphan (Robitussin)
  • Cepacol/Menthol throat lozenges
  • Vicks VapoRub


  • Increase fluid and fiber intake!!
  • Benefiber
  • Senna
  • Psyllium (Metamucil)
  • Docusate (Colace)
  • Magnesium Citrate
  • Polyethylene Glycol (Miralax)


  • Bland diet and increased hydration are best
  • If persistent, Imodium can be used sparingly.


  • Simethicone (Gas-X)


  • Tums
  • Rolaids
  • Mylanta
  • Famotidine (Pepcid)
  • Cemetidine (Tagamet)
  • Esomeprazole (Nexium)


  • Dramamine (Meclizine)
  • Diphenhydramine (Benadryl)
  • Unisom Sleep Tabs +/- Vitamin B6 (over the counter substitution for Diclegis)
  • Diclegis or Bonjesta—Rx only, speak with your provider
  • Metoclopramide (Reglan)–Rx only, speak with your provider
  • Ondansetron (Zofran)–Rx only, speak with your provider


  • Monistat 7 (miconozole)
  • Vagisil
  • Clindamycin—Rx only, speak with your provider
  • Metronidazole—Rx only, speak with your provider
  • Terazol—Rx only, speak with your provider

This list is not comprehensive. There are plenty other medications that are considered safe in pregnancy. Please contact us if you have questions or concerns!

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